Interferon Regulatory Factor-3

An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription.

Also Known As:

Interferon Regulatory Factor 3; IFN-Regulatory Factor 3; IFN Regulatory Factor 3; IRF 3 Transcription Factor; Transcription Factor, IRF-3; IRF-3 Transcription Factor

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Transcription Factors: 38804
    - Interferon Regulatory Factors: 701
      - Interferon Regulatory Factor-3: 439
  - Carrier Proteins: 12999
    - Signal Transducing Adaptor Proteins
      - Interferon Regulatory Factors: 701
        Interferon Regulatory Factor-3: 439
  - DNA-Binding Proteins: 2009
    - Interferon Regulatory Factors: 701
      - Interferon Regulatory Factor-3: 439
  - Phosphoproteins: 1772
    - Interferon Regulatory Factor-3: 439
  - Intracellular Signaling Peptides and Proteins: 32
    - Signal Transducing Adaptor Proteins
      - Interferon Regulatory Factors: 701
        Interferon Regulatory Factor-3: 439
- Peptides: 82426
  - Intracellular Signaling Peptides and Proteins: 32
    - Signal Transducing Adaptor Proteins
      - Interferon Regulatory Factors: 701
        Interferon Regulatory Factor-3: 439

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Nguyen Phan Research Topics

Disease

Drug/Important Bio-Agent (IBA)